Retrosynthesis ex machina

A Christmas present from one of the bastions of modern organic synthesis appeared in Nature. The idea of automated retrosynthetic analysis bugged the greatest OC minds since EJ Corey came up with the very concept of retrosynthesis. Back in 1969 Corey and Wipke set the stage by publishing a paper in Science.

corey_CAOS
Screenshot of the title and the whole abstract of the 1969 Science paper. Source

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